SAFETY AND EFFICACY OF MASS DRUG ADMINISTRATION WITH A SINGLE-DOSE TRIPLE-DRUG REGIMEN OF ALBENDAZOLE + DIETHYLCARBAMAZINE + IVERMECTIN FOR LYMPHATIC FILARIASIS IN PAPUA NEW GUINEA: AN OPEN-LABEL, CLUSTER-RANDOMISED TRIAL.

Safety and efficacy of mass drug administration with a single-dose triple-drug regimen of albendazole + diethylcarbamazine + ivermectin for lymphatic filariasis in Papua New Guinea: An open-label, cluster-randomised trial.

BackgroundPapua New Guinea (PNG) has a high burden of lymphatic filariasis (LF) caused by Wuchereria bancrofti, with an estimated 4.2 million people at risk of infection.A single co-administered dose of ivermectin, diethylcarbamazine and albendazole (IDA) has been shown to have superior efficacy in sustained clearance of microfilariae compared to d

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Hypothermia and temperature modulation for intracerebral hemorrhage (ICH): pathophysiology and translational applications

BackgroundIntracerebral hemorrhage (ICH) still poses a substantial challenge in clinical medicine because of the high morbidity and mortality rate that COFFEE LIONS MANE characterizes it.This review article expands into the complex pathophysiological processes underlying primary and secondary neuronal death following ICH.It explores the potential o

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